Biotin Anti-TCR alpha + TCR beta antibody [IP26] (ab95647)
Key features and details
- Biotin Mouse monoclonal [IP26] to TCR alpha + TCR beta
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
Overview
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Product name
Biotin Anti-TCR alpha + TCR beta antibody [IP26]
See all TCR alpha + TCR beta primary antibodies -
Description
Biotin Mouse monoclonal [IP26] to TCR alpha + TCR beta -
Host species
Mouse -
Conjugation
Biotin -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length protein corresponding to Human TCR alpha + TCR beta. Native protein
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Positive control
- Normal human peripheral blood cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
IP26 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab95647 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
0.5 µg/test |
Notes |
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Flow Cyt
Use at an assay dependent concentration. 0.5 µg/test |
Target
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Relevance
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. -
Cellular localization
Type I membrane protein. -
Database links
- Entrez Gene: 6955 Human
- Entrez Gene: 6957 Human
- Omim: 186880 Human
- Omim: 186930 Human
- SwissProt: P01848 Human
- SwissProt: P04435 Human
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Alternative names
- FLJ22602 antibody
- MGC117436 antibody
- MGC22624 antibody
see all
Images
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Staining of human peripheral blood mononuclear cells with CD45 Pacific Blue, CD3 FITC, CD19 PE and TCR alpha/beta Biotin followed by staining with APC conjugated streptavidin. As expected based on known relative expression patterns, TCR alpha/beta clone IP26 stains a subset of lymphocytes (pink), but not monocytes (orange) and granulocytes (blue).
Datasheets and documents
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Datasheet download
References (0)
ab95647 has not yet been referenced specifically in any publications.