Anti-TCR alpha + TCR beta antibody [TCR2] (Biotin) (ab25152)

Overview

  • Product nameAnti-TCR alpha + TCR beta antibody [TCR2] (Biotin)
    See all TCR alpha + TCR beta primary antibodies
  • Description
    Mouse monoclonal [TCR2] to TCR alpha + TCR beta (Biotin)
  • ConjugationBiotin
  • Specificityab25152 recognises Chicken TCR aß (Vß1).
  • Tested applicationsSuitable for: IP, Flow Cyt, Functional Studies, IHC-Frmore details
  • Species reactivity
    Reacts with: Chicken
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityIgG fraction
  • ClonalityMonoclonal
  • Clone numberTCR2
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab25152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
Flow Cyt
Functional Studies
IHC-Fr
  • Application notesFlow Cyt: Use <1µg for 106 cells.
    FuncS (In ovo suppression of the development of TCR-Vβ1 cells): Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
    • Cellular localizationType I membrane protein.
    • Alternative names
      • FLJ22602 antibody
      • MGC117436 antibody
      • MGC22624 antibody
      • MGC23964 antibody
      • MGC71411 antibody
      • T cell antigen receptor alpha polypeptide antibody
      • T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody
      • T cell receptor alpha (V D J C) antibody
      • T cell receptor alpha chain C region antibody
      • T cell receptor alpha constant antibody
      • T cell receptor alpha locus antibody
      • T cell receptor beta cluster antibody
      • T cell receptor beta locus antibody
      • TCRA antibody
      • TCRB antibody
      • TCRD antibody
      • TRA antibody
      • TRAC antibody
      • TRB antibody
      see all

    References for Anti-TCR alpha + TCR beta antibody [TCR2] (Biotin) (ab25152)

    This product has been referenced in:

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"