Anti-TCR gamma + TCR delta antibody [TCR1] (Phycoerythrin) (ab25423)

Overview

  • Product nameAnti-TCR gamma + TCR delta antibody [TCR1] (Phycoerythrin)
    See all TCR gamma + TCR delta primary antibodies
  • Description
    Mouse monoclonal [TCR1] to TCR gamma + TCR delta (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Specificityab25423 recognises TCR gamma and TCR delta.
  • Tested applicationsSuitable for: Flow Cyt, IP, IHC-Fr, Functional Studiesmore details
  • Species reactivity
    Reacts with: Chicken
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

Applications

Our Abpromise guarantee covers the use of ab25423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IP
IHC-Fr
Functional Studies
  • Application notesFlow Cyt: Use 0.2µg for 106 cells.
    FuncS: Use at an assay dependent dilution.
    ab25423 can be used for in ovo depletion of gd T cells.
    IHC-Fr: Use at an assay dependent dilution.
    Note: samples need to be acetone fixed.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceT cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one a and one b chain or one d and one g chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.
    • Cellular localizationType I membrane protein
    • Alternative names
      • CD_antigen=CD3d antibody
      • CD3D antibody
      • CD3G antibody
      • T cell antigen receptor delta polypeptide antibody
      • T cell antigen receptor gamma polypeptide antibody
      • T cell rearranging gene gamma antibody
      • T cell receptor delta antibody
      • T cell receptor delta locus antibody
      • T cell receptor gamma antibody
      • T cell receptor gamma chain C region PT gamma 1/2 antibody
      • T cell receptor gamma cluster antibody
      • T cell receptor gamma locus antibody
      • T cell receptor T3 delta chain antibody
      • T cell receptor, delta (V,D,J,C) antibody
      • T cell receptors antibody
      • T cell surface glycoprotein CD3 delta chain antibody
      • T-cell receptor T3 gamma chain antibody
      • T-cell surface glycoprotein CD3 gamma chain antibody
      • T3D antibody
      • T3G antibody
      • TCRD antibody
      • TCRDV1 antibody
      • TCRG antibody
      • TRD antibody
      • TRD locus antibody
      • TRD@ antibody
      • TRG antibody
      • TRG locus antibody
      • TRGC2 antibody
      see all

    Anti-TCR gamma + TCR delta antibody [TCR1] (Phycoerythrin) images

    • Flow cytometry analysis staining TCR gamma + TCR delta in chicken peripheral blood mononuclear cells using ab25423 at a dilution of 0.1 ug/106 cells.

    References for Anti-TCR gamma + TCR delta antibody [TCR1] (Phycoerythrin) (ab25423)

    ab25423 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab25423.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"