Anti-TDRD3 antibody (ab169059)
Key features and details
- Mouse polyclonal to TDRD3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TDRD3 antibody
See all TDRD3 primary antibodies -
Description
Mouse polyclonal to TDRD3 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat, Cow, Chimpanzee, Cynomolgus monkey, Rhesus monkey -
Immunogen
Recombinant full length protein within Human TDRD3 aa 1-700. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- TDRD3 transfected 293T cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab169059 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa. |
Target
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Function
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. -
Tissue specificity
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. -
Sequence similarities
Contains 1 Tudor domain.
Contains 1 UBA domain. -
Domain
The Tudor domain specifically recognizes and binds asymmetric dimethylation of histone H3 'Arg-17' (H3R17me2a) and histones H4 'Arg-3', 2 tags for epigenetic transcriptional activation. -
Cellular localization
Cytoplasm. Nucleus. Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules. - Information by UniProt
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Database links
- Entrez Gene: 452750 Chimpanzee
- Entrez Gene: 537918 Cow
- Entrez Gene: 81550 Human
- Entrez Gene: 306066 Rat
- Omim: 614392 Human
- SwissProt: Q2HJG4 Cow
- SwissProt: Q9H7E2 Human
- SwissProt: Q66HC1 Rat
see all -
Alternative names
- 4732418C03Rik antibody
- 6720468N18 antibody
- FLJ21007 antibody
see all
Images
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All lanes : Anti-TDRD3 antibody (ab169059) at 1 µg/ml
Lane 1 : TDRD3 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 73 kDa
Datasheets and documents
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Datasheet download
References (0)
ab169059 has not yet been referenced specifically in any publications.