Overview

  • Product name
    Anti-TdT antibody [41A]
    See all TdT primary antibodies
  • Description
    Mouse monoclonal [41A] to TdT
  • Tested applications
    Suitable for: IHC-P, ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein

  • Positive control
    • Thymus.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • Purity
    IgG fraction
  • Purification notes
    This antibody was purified using a AKTA prime.
  • Clonality
    Monoclonal
  • Clone number
    41A
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab68886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.
ELISA 1/1000.
WB 1/100. Detects a band of approximately 60 kDa (predicted molecular weight: 58 kDa).

Target

  • Function
    Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
  • Sequence similarities
    Belongs to the DNA polymerase type-X family.
    Contains 1 BRCT domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deoxynucleotidyltransferase terminal antibody
    • DNA nucleotidylexotransferase antibody
    • DNTT antibody
    • Nucleosidetriphosphate DNA deoxynucleotidylexotransferase antibody
    • TDT antibody
    • TDT_HUMAN antibody
    • Terminal addition enzyme antibody
    • Terminal deoxynucleotidyltransferase antibody
    • Terminal deoxyribonucleotidyltransferase antibody
    • Terminal transferase antibody
    see all

Anti-TdT antibody [41A] images

  • Anti-TdT antibody [41A] (ab68886) at 1/100 dilution + Thymus extracts

    Predicted band size : 58 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
  • Ab68886 (1:100) staining human TdT in human thymus by immunohistochemistry using formalin fixed, paraffin embedded tissue.
  • Ab68886 (1:100) staining TdT in human thymus tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

References for Anti-TdT antibody [41A] (ab68886)

This product has been referenced in:
  • McClory S  et al. Evidence for a stepwise program of extrathymic T cell development within the human tonsil. J Clin Invest 122:1403-15 (2012). IHC ; Human . Read more (PubMed: 22378041) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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