Overview

  • Product nameAnti-TECPR1 antibody
    See all TECPR1 primary antibodies
  • Description
    Rabbit polyclonal to TECPR1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Aa KLH conjugated synthetic peptide selected from the C-terminal region of Human TECPR1 (NP_056210.1)

  • Positive control
    • Mouse brain tissue lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityAmmonium Sulphate Precipitation
  • Purification notesSaturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab91234 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/50 - 1/100. Predicted molecular weight: 130 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionTethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
    • Sequence similaritiesBelongs to the TECPR1 family.
      Contains 1 PH domain.
      Contains 9 TECPR repeats.
    • DomainThe PH domain mediates the binding to phosphatidylinositol-3-phosphate (PtdIns(3)P). While full-length protein is unable to bind PtdIns(3)P in vitro, it is assumed that the binding to the ATG5-ATG12 conjugate exposes the PH domain, allowing the association with PtdIns(3)P (PubMed:22342342).
    • Cellular localizationCytoplasmic vesicle > autophagosome membrane. Lysosome membrane. Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2210010N04Rik antibody
      • DKFZP434B0335 antibody
      • FLJ23419 antibody
      • FLJ90593 antibody
      • KIAA1358 antibody
      • MGC124730 antibody
      • mKIAA1358 antibody
      • RGD1306873 antibody
      • TCPR1_HUMAN antibody
      • Tecpr1 antibody
      • tectonin beta propeller repeat containing 1 antibody
      • Tectonin beta-propeller repeat-containing protein 1 antibody
      see all

    Anti-TECPR1 antibody images

    • Anti-TECPR1 antibody (ab91234) at 1/50 dilution + Mouse brain tissue lysate at 35 µg

      Predicted band size : 130 kDa

    References for Anti-TECPR1 antibody (ab91234)

    ab91234 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab91234.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"