Overview

  • Product name
  • Description
    Rabbit polyclonal to TECPR1
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Aa KLH conjugated synthetic peptide selected from the C-terminal region of Human TECPR1 (NP_056210.1)

  • Positive control
    • Mouse brain tissue lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Ammonium Sulphate Precipitation
  • Purification notes
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab91234 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/1000.
    WB: 1/50 - 1/100. Predicted molecular weight: 130 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
    • Sequence similarities
      Belongs to the TECPR1 family.
      Contains 1 PH domain.
      Contains 9 TECPR repeats.
    • Domain
      The PH domain mediates the binding to phosphatidylinositol-3-phosphate (PtdIns(3)P). While full-length protein is unable to bind PtdIns(3)P in vitro, it is assumed that the binding to the ATG5-ATG12 conjugate exposes the PH domain, allowing the association with PtdIns(3)P (PubMed:22342342).
    • Cellular localization
      Cytoplasmic vesicle > autophagosome membrane. Lysosome membrane. Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2210010N04Rik antibody
      • DKFZP434B0335 antibody
      • FLJ23419 antibody
      • FLJ90593 antibody
      • KIAA1358 antibody
      • MGC124730 antibody
      • mKIAA1358 antibody
      • RGD1306873 antibody
      • TCPR1_HUMAN antibody
      • Tecpr1 antibody
      • tectonin beta propeller repeat containing 1 antibody
      • Tectonin beta-propeller repeat-containing protein 1 antibody
      see all

    Anti-TECPR1 antibody images

    • Anti-TECPR1 antibody (ab91234) at 1/50 dilution + Mouse brain tissue lysate at 35 µg

      Predicted band size : 130 kDa

    References for Anti-TECPR1 antibody (ab91234)

    ab91234 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab91234.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up