• Product nameAnti-TECTA antibody
  • Description
    Mouse monoclonal to TECTA
  • Tested applicationsSuitable for: WB, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment corresponding to amino acids 1981-2081 of Human TECTA (NP_005413), with proprietary tag. Mol wt 37.11 kDa inclusive of tag.

  • Positive control
    • Recombinant protein


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab118086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 240 kDa.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent concentration.


  • FunctionOne of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
  • Involvement in diseaseDefects in TECTA are the cause of deafness autosomal dominant type 12 (DFNA12) [MIM:601543]; also known as DFNA8. DFNA12 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    Defects in TECTA are the cause of deafness autosomal recessive type 21 (DFNB21) [MIM:603629].
  • Sequence similaritiesContains 1 NIDO domain.
    Contains 3 TIL (trypsin inhibitory-like) domains.
    Contains 1 VWFC domain.
    Contains 4 VWFD domains.
    Contains 1 ZP domain.
  • DomainZona pellucida domain may enable to form filaments.
  • Post-translational
    The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia by the lipid and proteolytically released into the extracellular compartment.
  • Cellular localizationCell membrane. Secreted > extracellular space > extracellular matrix. Found in the non-collagenous matrix of the tectorial membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha-tectorin antibody
    • DFNA12 antibody
    • DFNA8 antibody
    • DFNB21 antibody
    • OTTHUMP00000195078 antibody
    • TECTA antibody
    • TECTA_HUMAN antibody
    see all

Anti-TECTA antibody images

  • Anti-TECTA antibody (ab118086) at 1 µg/ml + Recombinant Protein at 0.1 µg
    Developed using the ECL technique

    Predicted band size : 240 kDa
  • Detection limit for recombinant proprietary tagged TECTA is 0.3 ng/ml as a capture antibody.

References for Anti-TECTA antibody (ab118086)

ab118086 has not yet been referenced specifically in any publications.

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