Anti-TECTB antibody (ab107722)

Overview

  • Product nameAnti-TECTB antibody
  • Description
    Rabbit polyclonal to TECTB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide designed between amino acids 61-91 from the N-terminal region of Human TECTB (NP_478129.1)

  • Positive control
    • Mouse stomach tissue lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab107722 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 37 kDa.

Target

  • FunctionOne of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
  • Sequence similaritiesContains 1 ZP domain.
  • DomainZona pellucida domain may enable to form filaments.
  • Post-translational
    modifications
    The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia by the lipid and proteolytically released into the extracellular compartment.
  • Cellular localizationCell membrane. Secreted > extracellular space > extracellular matrix. Found in the non-collagenous matrix of the tectorial membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beta-tectorin antibody
    • KIAA1560 antibody
    • MGC142057 antibody
    • MGC142059 antibody
    • Tectb antibody
    • TECTB_HUMAN antibody
    • Tectorin beta antibody
    see all

Anti-TECTB antibody images

  • Anti-TECTB antibody (ab107722) at 1/100 dilution + Mouse stomach tissue lysates at 35 µg

    Predicted band size : 37 kDa

References for Anti-TECTB antibody (ab107722)

ab107722 has not yet been referenced specifically in any publications.

Product Wall

Thank you for providing an Abreview for ab107722 Anti-TECTB antibody.

I am sorry to see that this product did not perform as expected in WB on mouse stomach samples. We guarantee our products to work as stated on the datasheet and would apprec...

Read More
Abreviews
Application Western blot
Sample Mouse Tissue lysate - whole (Stomach)
Loading amount 40 µg
Specification Stomach
Gel Running Conditions Reduced Non-Denaturing (Native) (10% Tris-Glycine)
Blocking step BSA as blocking agent for 12 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Mr. James Bjork

Verified customer

Submitted Dec 04 2012

Abreviews
Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Spermophilus tridecemlineatus Tissue lysate - whole (Cochlea)
Loading amount 40 µg
Specification Cochlea
Gel Running Conditions Reduced Denaturing (10% Tris-Glycine)
Blocking step BSA as blocking agent for 12 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Mr. James Bjork

Verified customer

Submitted Dec 03 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"