Recombinant
RabMAb

Anti-Telomerase reverse transcriptase antibody [Y182] (ab32020)

Publishing research using ab32020? Please let us know so that we can cite the reference in this datasheet.

ab32020 has been referenced in 40 publications.

  • Im E  et al. Human Telomerase Reverse Transcriptase (hTERT) Positively Regulates 26S Proteasome Activity. J Cell Physiol N/A:N/A (2016). PubMed: 27648923
  • Yang Y  et al. MR molecular imaging of tumours using ferritin heavy chain reporter gene expression mediated by the hTERT promoter. Eur Radiol 26:4089-4097 (2016). PubMed: 26960542
  • Bisht K  et al. Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc Natl Acad Sci U S A 113:13021-13026 (2016). ChIP . PubMed: 27807141
  • Eitan E  et al. Expression of functional alternative telomerase RNA component gene in mouse brain and in motor neurons cells protects from oxidative stress. Oncotarget 7:78297-78309 (2016). IP ; Mouse . PubMed: 27823970
  • Yang H  et al. Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells. J Cancer 7:1152-62 (2016). WB . PubMed: 27326259
  • Gao X  et al. UBE2D3 gene overexpression increases radiosensitivity of EC109 esophageal cancer cells in vitro and in vivo. Oncotarget 7:32543-53 (2016). PubMed: 27105523
  • Kellermann G  et al. Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT. Nucleic Acids Res 43:e99 (2015). PubMed: 25958399
  • Yu WY  et al. Bovine posterior limbus: an evaluation of an alternative source for corneal endothelial and trabecular meshwork stem/progenitor cells. Stem Cells Dev 24:624-39 (2015). PubMed: 25323922
  • Koh CM  et al. Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest 125:2109-22 (2015). WB, ChIP ; Human . PubMed: 25893605
  • Guan GG  et al. UBE2D3 is a positive prognostic factor and is negatively correlated with hTERT expression in esophageal cancer. Oncol Lett 9:1567-1574 (2015). IHC . PubMed: 25789002
  • Li Y  et al. Non-canonical NF-?B signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. Nat Cell Biol 17:1327-38 (2015). PubMed: 26389665
  • Huang Y  et al. Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability. J Biol Chem 290:18865-73 (2015). PubMed: 26070557
  • Xi L  et al. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol 16:231 (2015). Human . PubMed: 26553065
  • Panneer Selvam S  et al. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal 8:ra58 (2015). PubMed: 26082434
  • Spilsbury A  et al. The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro. J Neurosci 35:1659-74 (2015). PubMed: 25632141
  • Xi L & Cech TR Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT. Nucleic Acids Res 42:8565-77 (2014). WB . PubMed: 24990373
  • Diaz A  et al. TERT and AURKA gene copy number gains enhance the detection of acral lentiginous melanomas by fluorescence in situ hybridization. J Mol Diagn 16:198-206 (2014). IHC . PubMed: 24374110
  • Yuan P  et al. Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G1 cell cycle arrest in A549 cells. Oncol Lett 8:1009-1016 (2014). WB, ICC/IF ; Human . PubMed: 25120649
  • Hwang H  et al. Single-molecule real-time detection of telomerase extension activity. Sci Rep 4:6391 (2014). FRET . PubMed: 25263700
  • Schmidt JC  et al. Identification of human TERT elements necessary for telomerase recruitment to telomeres. Elife 3:N/A (2014). PubMed: 25271372
  • Kasiappan R  et al. Vitamin D suppresses leptin stimulation of cancer growth through microRNA. Cancer Res 74:6194-204 (2014). PubMed: 25252917
  • Jung AR  et al. Increased alternative lengthening of telomere phenotypes of telomerase-negative immortal cells upon trichostatin--a treatment. Anticancer Res 33:821-9 (2013). WB ; Human . PubMed: 23482750
  • Zaug AJ  et al. Many disease-associated variants of hTERT retain high telomerase enzymatic activity. Nucleic Acids Res N/A:N/A (2013). WB . PubMed: 23901009
  • Yang K  et al. p38? overexpression in gliomas and its role in proliferation and apoptosis. Sci Rep 3:2089 (2013). WB ; Human . PubMed: 23807566
  • Hirashima K  et al. Telomere length influences cancer cell differentiation in vivo. Mol Cell Biol 33:2988-95 (2013). WB, IF, In situ hybridization . PubMed: 23716593
  • Shen T  et al. Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension. PLoS One 8:e83132 (2013). IHC-P, ICC/IF ; Rat, Human . PubMed: 24376652
  • Benko AL  et al. Estrogen and telomerase in human peripheral blood mononuclear cells. Mol Cell Endocrinol 364:83-8 (2012). PubMed: 22954679
  • He Z  et al. Revisited microanatomy of the corneal endothelial periphery: new evidence for continuous centripetal migration of endothelial cells in humans. Stem Cells 30:2523-34 (2012). IHC - Wholemount ; Human . PubMed: 22949402
  • Kar A  et al. Metastases suppressor NME2 associates with telomere ends and telomerase and reduces telomerase activity within cells. Nucleic Acids Res 40:2554-65 (2012). WB, ICC/IF ; Human . PubMed: 22135295
  • Righolt CH  et al. Robust nuclear lamina-based cell classification of aging and senescent cells. Aging (Albany NY) 3:1192-201 (2011). WB, ICC/IF ; Human . PubMed: 22199022
  • Chen J  et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Res 71:4138-49 (2011). Human . PubMed: 21527554
  • Janson C  et al. Immortalization and functional characterization of rat arachnoid cell lines. Neuroscience 177:23-34 (2011). WB, ICC/IF ; Human . PubMed: 21195136
  • Han JB  et al. Adenovirus-mediated transfer of tris-shRNAs induced apoptosis of nasopharyngeal carcinoma cell in vitro and in vivo. Cancer Lett 309:162-9 (2011). WB ; Human . PubMed: 21669490
  • Hsin IL  et al. N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells. Mutat Res 688:72-77 (2010). PubMed: 20363232
  • Cai MY  et al. Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma. Cancer Sci 101:1543-9 (2010). IHC-P ; Human . PubMed: 20367640
  • Wang S  et al. TGF-beta1 signal pathway may contribute to rhabdomyosarcoma development by inhibiting differentiation. Cancer Sci 101:1108-16 (2010). IHC-P ; Human . PubMed: 20219075
  • Benson EK  et al. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. J Cell Sci 123:2605-12 (2010). WB ; Human . PubMed: 20605919
  • Romanova L  et al. Novel role of nucleostemin in the maintenance of nucleolar architecture and integrity of small nucleolar ribonucleoproteins and the telomerase complex. J Biol Chem 284:26685-94 (2009). WB ; Human . PubMed: 19648109
  • Lin G  et al. Defining stem and progenitor cells within adipose tissue. Stem Cells Dev 17:1053-63 (2008). PubMed: 18597617
  • McGowan SL  et al. Stem cell markers in the human posterior limbus and corneal endothelium of unwounded and wounded corneas. Mol Vis 13:1984-2000 (2007). IHC-Fr ; Human . PubMed: 17982423

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up