Overview

  • Product nameAnti-TEM1 antibody
    See all TEM1 primary antibodies
  • Description
    Rabbit polyclonal to TEM1
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A 14 amino acid synthetic peptide near the C terminus of Human TEM1.

  • Positive control
    • Human pancreas tissue; Human colon tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab115870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 81 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMay play a role in tumor angiogenesis.
  • Tissue specificityExpressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
  • Sequence similaritiesContains 1 C-type lectin domain.
    Contains 1 EGF-like domain.
    Contains 1 Sushi (CCP/SCR) domain.
  • Post-translational
    modifications
    O-glycosylated with sialylated oligosaccharides.
    May be N-glycosylated.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD164 sialomucin like 1 antibody
    • CD164L1 antibody
    • CD248 antibody
    • CD248 antigen endosialin antibody
    • CD248 molecule endosialin antibody
    • CD248_HUMAN antibody
    • Endosialin antibody
    • TEM 1 antibody
    • TEM1 antibody
    • Tumor endothelial marker 1 antibody
    see all

Anti-TEM1 antibody images

  • ab115870, at 5 ug/ml, staining TEM1 in Formalin-fixed, Paraffin-embedded Human pancreas tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Lane 1 : Anti-TEM1 antibody (ab115870) at 0.5 µg/ml
    Lane 2 : Anti-TEM1 antibody (ab115870) at 1 µg/ml

    Lane 1 : Human colon tissue lysate
    Lane 2 : Human colon tissue lysate


    Predicted band size : 81 kDa

References for Anti-TEM1 antibody (ab115870)

ab115870 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"