Overview

  • Product nameAnti-TEM7 antibody
    See all TEM7 primary antibodies
  • Description
    Rabbit polyclonal to TEM7
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a 16 amino acid sequence near the center of Human TEM7.

  • Positive control
    • Human kidney tissue; Rat liver lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab118874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 56 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionPlays a critical role in endothelial cell capillary morphogenesis.
  • Tissue specificityDetected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy.
  • Sequence similaritiesBelongs to the plexin family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCytoplasm; Secreted and Cell membrane. Cell junction > tight junction. Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686F0937 antibody
    • FLJ36270 antibody
    • FLJ45632 antibody
    • OTTHUMP00000164240 antibody
    • Plexin domain containing 1 antibody
    • Plexin domain containing protein 1 precursor antibody
    • Plexin domain-containing protein 1 antibody
    • Plxdc1 antibody
    • PXDC1_HUMAN antibody
    • TEM3 antibody
    • TEM7 antibody
    • Tumor endothelial marker 3 antibody
    • Tumor endothelial marker 7 antibody
    see all

Anti-TEM7 antibody images

  • Lane 1 : Anti-TEM7 antibody (ab118874) at 0.5 µg/ml
    Lane 2 : Anti-TEM7 antibody (ab118874) at 1 µg/ml

    Lane 1 : Rat liver lysate
    Lane 2 : Rat liver lysate


    Predicted band size : 56 kDa
  • ab118874, at 5 µg/ml, staining TEM7 in formalin fixed, paraffin embedded Human kidney tissue by Immunohistochemistry. This was followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-TEM7 antibody (ab118874)

ab118874 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"