Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab52008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/2000. Peptide ELISA
ICC Use a concentration of 4 - 6 µg/ml.

Target

  • FunctionInvolved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 C2 tensin-type domain.
    Contains 1 phosphatase tensin-type domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    Rapidly cleaved by calpain II.
  • Cellular localizationCell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
  • Information by UniProt
  • Database links
  • Alternative names
    • matrix-remodelling associated 6 antibody
    • Matrix-remodelling-associated protein 6 antibody
    • MGC88584 antibody
    • MST091 antibody
    • MST122 antibody
    • MST127 antibody
    • MSTP091 antibody
    • MSTP122 antibody
    • MSTP127 antibody
    • MXRA6 antibody
    • TENS1_HUMAN antibody
    • Tensin antibody
    • Tensin-1 antibody
    • TNS antibody
    • TNS1 antibody
    see all

Anti-Tensin 1 antibody images

  • ab52008 (4µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining shows weak staining of the basement membranes of convoluted tubules.

References for Anti-Tensin 1 antibody (ab52008)

ab52008 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"