Potent, selective blocker of Kir1.1 channels. Tertiapin Q (ab120432) derivative.
Biological descriptionTertiapin Q (ab120432) derivative. Potent, selective blocker of Kir1.1 channels. Shows greater than >250-fold selectivity for Kir1.1 over Kir3.1/3.4 (Kd values are 1.3 and 274 nM at Kir1.1 and Kir3.1/3.4, respectively). Displays greater selectivity at Kir1.1 than Tertiapin Q (ab120432).
General notesSold under license granted by the University of Pennsylvania.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.