The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceFolic acid and folate (the anion form) are forms of a water-soluble B vitamin. Folate is necessary for the production and maintenance of new cells.This is especially important during periods of rapid cell division and growth such as infancy and pregnancy. Folate is needed to replicate DNA. It also helps prevent changes to DNA that may lead to cancer.
The coenzyme Tetrahydrofolic Acid (THFA) is derived in humans from folic acid.
The pathway in the formation of tetrahydrofolate (FH4) is the reduction of folate (F) to dihydrofolate (FH2) and then the subsequent reduction of dihydrofolate to tetrahydrofolate (FH4). Both these sequential reactions are carried out by dihydrofolate reductase.
This coenzyme and its close relatives participate in the transfer of various carbon fragments from one molecule to another; they are, for instance, involved in the synthesis of methionine and thymine and also are involved in the synthesis of dTMP (2'-deoxythymidine-5'-phosphate) from dUMP (2'-deoxyuridine-5'-phosphate).
Cellular localizationCell membrane
folic acid antibody
Vitamin B9 antibody
References for Anti-Tetrahydrofolic Acid antibody (ab31502)
has not yet been referenced specifically in any publications.
Publishing research using ab31502? Please let us know so that we can cite the reference in this datasheet.
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