Overview

  • Product name
  • Description
    Rabbit polyclonal to TFIIS
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a sequence between internal sequence amino acids 85-115 of Human TFIIS (NP_003186.1, NP_942016.1).

  • Positive control
    • U251 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab124107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.

Target

  • Function
    Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
  • Tissue specificity
    Testis and ovary specific.
  • Sequence similarities
    Belongs to the TFS-II family.
    Contains 1 TFIIS central domain.
    Contains 1 TFIIS N-terminal domain.
    Contains 1 TFIIS-type zinc finger.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Tcea2 antibody
    • TCEA2_HUMAN antibody
    • Testis specific S II antibody
    • Testis-specific S-II antibody
    • TFIIS antibody
    • Transcription elongation factor A (SII) 2 antibody
    • Transcription elongation factor A 2 antibody
    • Transcription elongation factor A protein 2 antibody
    • Transcription elongation factor S II protein 2 antibody
    • Transcription elongation factor S-II protein 2 antibody
    • Transcription elongation factor TFIIS.1 antibody
    • Transcription elongation factor TFIIS.l antibody
    see all

Images

  • Anti-TFIIS antibody (ab124107) at 1/100 dilution + U251 cell line lysates at 35 µg

    Predicted band size : 34 kDa

References

ab124107 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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