Overview

  • Product nameAnti-TFPI2 antibody
    See all TFPI2 primary antibodies
  • Description
    Rabbit polyclonal to TFPI2
  • SpecificityNo cross reactivity with other proteins.
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A synthetic peptide corresponding to internal sequence of Human TFPI2

  • Positive control
    • Rat brain and pancreas tissue lysates; MM453, MM231, HeLa, HT1080 and Jurkat whole cell lysates; Human mammary cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab86933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.
IHC-P Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • FunctionMay play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.
  • Tissue specificityUmbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.
  • Sequence similaritiesContains 3 BPTI/Kunitz inhibitor domains.
  • DomainThis inhibitor contains three inhibitory domains.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Placental protein 5 antibody
    • PP5 antibody
    • REF1 antibody
    • Retinal pigment epithelium cell factor 1 antibody
    • TFPI 2 antibody
    • TFPI-2 antibody
    • TFPI2 antibody
    • TFPI2 PEN antibody
    • TFPI2_HUMAN antibody
    • Tissue factor pathway inhibitor 2 antibody
    see all

Anti-TFPI2 antibody images

  • ab86933, at 2µg/ml, staining paraffin-embedded Human Mammary cancer tissue by Immunohistochemistry.
  • All lanes : Anti-TFPI2 antibody (ab86933) at 1 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat pancreas tissue lysate
    Lane 3 : MM453 whole cell lysate
    Lane 4 : MM231 whole cell lysate
    Lane 5 : HeLa whole cell lysate
    Lane 6 : HT1080 whole cell lysate
    Lane 7 : Jurkat whole cell lysate


    Predicted band size : 27 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)

References for Anti-TFPI2 antibody (ab86933)

ab86933 has not yet been referenced specifically in any publications.

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