Overview

  • Product name
    Anti-TFPT antibody - N-terminal
    See all TFPT primary antibodies
  • Description
    Rabbit polyclonal to TFPT - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide within Human TFPT aa 67-97 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P0C1Z6

  • Positive control
    • MDA-MB435 cells and cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab176167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 28 kDa.
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Appears to promote apoptosis in a p53/TP53-independent manner.
    Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
  • Involvement in disease
    Note=A chromosomal aberration involving TFPT is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Inversion inv(19)(p13;q13) with TCF3.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amida antibody
    • INO80 complex subunit F antibody
    • INO80F antibody
    • Protein FB1 antibody
    • TCF3 (E2A) fusion partner (in childhood Leukemia) antibody
    • TCF3 fusion partner antibody
    • TFPT antibody
    • TFPT_HUMAN antibody
    see all

Images

  • Flow cytometric analysis of MDA-MB435 cells labelling TFPT using ab176167 at 1/10 (bottom histogram) or negative control (top histogram)

  • Anti-TFPT antibody - N-terminal (ab176167) at 1/1000 dilution + MDA-MB435 cell lysate at 35 µg

    Predicted band size: 28 kDa

References

ab176167 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab176167.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up