Anti-TGF beta induced factor 2 antibody (ab123740)

Overview

  • Product name
    Anti-TGF beta induced factor 2 antibody
    See all TGF beta induced factor 2 primary antibodies
  • Description
    Rabbit polyclonal to TGF beta induced factor 2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 170-199 of Human TGF beta induced factor 2 (NP_068581.1).

  • Positive control
    • MDA-MB453 and Mouse Neuro 2a cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab123740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 26 kDa.

Target

  • Function
    Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
  • Tissue specificity
    Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
  • Sequence similarities
    Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
  • Cellular localization
    Nucleus. Excluded from nucleoli.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5' TG 3' interacting factor 2 antibody
    • 5''-TG-3''-interacting factor 2 antibody
    • Homeobox protein TGIF2 antibody
    • TGF (beta) induced transcription factor 2 antibody
    • TGF-beta-induced transcription factor 2 antibody
    • TGFB induced factor 2 antibody
    • TGFB-induced factor 2 antibody
    • Tgif2 antibody
    • TGIF2_HUMAN antibody
    • Transforming growth factor beta induced factor 2 antibody
    see all

Images

  • Anti-TGF beta induced factor 2 antibody (ab123740) at 1/100 dilution + MDA-MB453 cell line lysates at 35 µg

    Predicted band size : 26 kDa
  • Anti-TGF beta induced factor 2 antibody (ab123740) at 1/100 dilution + Mouse Neuro 2a cell line lysates at 35 µg

    Predicted band size : 26 kDa

References

ab123740 has not yet been referenced specifically in any publications.

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