Anti-TGF beta induced factor 2 antibody (ab39998)

Overview

  • Product name
    Anti-TGF beta induced factor 2 antibody
    See all TGF beta induced factor 2 primary antibodies
  • Description
    Goat polyclonal to TGF beta induced factor 2
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide:

    EMELQKQQDP

    , corresponding to C terminal amino acids 211-220 of Human TGF beta induced factor 2

  • Positive control
    • A431, A549 and HEK293 cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab39998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 26 kDa).
ELISA 1/16000.

Target

  • Function
    Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
  • Tissue specificity
    Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
  • Sequence similarities
    Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
  • Cellular localization
    Nucleus. Excluded from nucleoli.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5' TG 3' interacting factor 2 antibody
    • 5''-TG-3''-interacting factor 2 antibody
    • Homeobox protein TGIF2 antibody
    • TGF (beta) induced transcription factor 2 antibody
    • TGF-beta-induced transcription factor 2 antibody
    • TGFB induced factor 2 antibody
    • TGFB-induced factor 2 antibody
    • Tgif2 antibody
    • TGIF2_HUMAN antibody
    • Transforming growth factor beta induced factor 2 antibody
    see all

Images

References

ab39998 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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