Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (ab166705)
Key features and details
- Mouse monoclonal [1C5H11] to TGF beta Receptor III/TGFBR3
- Suitable for: WB, ELISA
- Reacts with: Mouse, Human, Recombinant fragment
- Isotype: IgG1
Overview
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Product name
Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11]
See all TGF beta Receptor III/TGFBR3 primary antibodies -
Description
Mouse monoclonal [1C5H11] to TGF beta Receptor III/TGFBR3 -
Host species
Mouse -
Tested applications
Suitable for: WB, ELISAmore details -
Species reactivity
Reacts with: Mouse, Human, Recombinant fragment
Predicted to work with: Chimpanzee, Orangutan -
Immunogen
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Recombinant Human TGF beta Receptor III/TGFBR3 protein; Jurkat, HeLa, MCF7, F9, SK N SH, NIH 3T3 cell lysates.
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General notes
This product was changed from ascites to supernatant. Lot no’s high than GR206347-9 are from Tissue Culture Supernatant.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: 99% PBS
Contains 0.5% protein stabilizer -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
1C5H11 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab166705 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 93 kDa.
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ELISA |
1/10000.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 93 kDa. |
ELISA
1/10000. |
Target
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Function
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. -
Sequence similarities
Contains 1 ZP domain. -
Post-translational
modificationsExtensively modified by glycosaminoglycan groups (GAG). -
Cellular localization
Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. - Information by UniProt
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Database links
- Entrez Gene: 7049 Human
- Entrez Gene: 21814 Mouse
- Omim: 600742 Human
- SwissProt: Q03167 Human
- SwissProt: O88393 Mouse
- Unigene: 482390 Human
- Unigene: 200775 Mouse
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Alternative names
- Beta glycan antibody
- Betaglycan antibody
- Betaglycan proteoglycan antibody
see all
Images
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Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (ab166705) at 1/500 dilution + recombinant Human TGF beta Receptor III/TGFBR3 protein
Predicted band size: 93 kDa
Expected MW of recombinant protein is 44.1 kDa. -
All lanes : Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (ab166705) at 1/500 dilution
Lane 1 : Jurkat cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : MCF7 cell lysate
Lane 4 : F9 cell lysate
Lane 5 : SK N SH cell lysate
Lane 6 : NIH 3T3 cell lysate
Predicted band size: 93 kDa -
ELISA using ab166705 at 1/10000 dilution
Red: Control Antigen (100 ng)
Purple: Antigen (10 ng)
Green: Antigen (50 ng)
Blue: Antigen (100 ng)
Datasheets and documents
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Datasheet download
References (3)
ab166705 has been referenced in 3 publications.
- Hao X & Wei H LncRNA H19 alleviates sepsis-induced acute lung injury by regulating the miR-107/TGFBR3 axis. BMC Pulm Med 22:371 (2022). PubMed: 36180862
- Roux SL et al. Transforming Growth Factor Beta 1 Modulates the Functional Expression of the Neurokinin-1 Receptor in Human Keratocytes. Curr Eye Res 41:1035-1043 (2016). PubMed: 26673553
- Zuckerwise L et al. H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TßR3 in placentae with fetal growth restriction. Oncotarget 7:38398-38407 (2016). PubMed: 27223264