Anti-TGF beta Receptor III antibody (ab10854)

Overview

  • Product nameAnti-TGF beta Receptor III antibody
    See all TGF beta Receptor III primary antibodies
  • Description
    Goat polyclonal to TGF beta Receptor III
  • SpecificityRecognizes the extracellular domain of human TGFBR3. By ELISA, the antibody shows no cross-reactivity with other cytokines tested: rhANG, rhAR, rhB7-1, rhB7-2, rmB7-2, rhBTC, rhb-NGF, rhBDNF, rmC10, rhCD4, rhCD8, rhCD28, rhCNTF, rrCNTF, rhEGF, rhENA-78, rhEpo, rhFGF acidic, rhFGF basic, rhFGF-4, rhFGF-5, rhFGF-6, rhFGF-7, rhFGF-9, rhG-CSF, rmG-CSF, rhGM-CSF, rhGM-CSF Ralpha, rmGM-CSF, rhGROalpha, rhGRObeta, rhGROgamma, rhHB-EGF, rhHRG-alpha, rhHGF, rhI-309, rhIFN-g, rhIGF-I, rhIGF-I R, rhIGF-II, rhIL-1alpha, rhIL-1 RI, rhIL-1 RII, rmIL-1alpha, rhIL-1beta, rmIL-1beta, rhIL-1ra, rmIL-1ra, rhIL-2, rhIL-2 sRalpha, rhIL-2 sRbeta, IL-2 sRgamma, rmIL-2, rhIL-3, rhIL-3 sRalpha, rmIL-3, rhIL-4, rhIL-4 sR, rmIL-4, rhIL-5, rhIL-5 sRalpha, rhIL-5 sRbeta, rmIL-5, rhIL-6, rhIL-6 sR, rmIL-6, rhIL-7, rhIL-7 R, rmIL-7, rhIL-8, rhIL-9, rmIL-9, rhIL-10, rhIL-10 sR, rmIL-10, rhIL-11, rhIL-12, rmIL-12, rhIL-13, rmIL-13, rhIL-15, rhIP-10, rhJAK-1, rmJAK-1, rmJE, rhLIF, rhLIF R, rmLIF, rhM-CSF, rmM-CSF, rhMCP-1, rhMCP-1 R, rhMCP-2, rhMCP-3, rhMidkine, rhMIP-1alpha, rmMIP-1alpha, rhMIP-1beta, rmMIP-1beta, rmMIP-2, rhNT-3, rhNT-4, rhOSM, rhPD-ECGF, hPDGF, pPDGF, rhPDGF-AA, rhPDGF-AB, rhPDGF-BB, rhPDGF Ralpha, rhPIGF, rhPTN, rhRANTES, rhSCF, rmSCF, rhsgp130, rhSLPI, rhSTAT-1, rmSTAT-4, hTfR, rhTGF-alpha, rhTGF-beta1, rhTGF-beta2, rhTGF-beta3, raTGF-beta5, rhLAP (TGF-beta1), rhLatent TGF-beta1, rhTGF-beta sRII, rhTNF-alpha, rmTNF-alpha, rhTNF-beta, rhsTNF RI, rhsTNF RII, rhTPO, rhVEGF
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human soluble TGFBR3, expressed in NSO cells.

  • Positive control
    • Recombinant human TGF beta soluble RIII. Any cells that express the protein should be suitable. The purified form of the protein may also be used to verify detection. Please note that since this protein is soluble, carefull analysis of the culture supernatant should be done.
  • General notesEndotoxin level is < 10 ng per mg antibody as determined by the LAL method.

Properties

Applications

Our Abpromise guarantee covers the use of ab10854 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.5 - 1 µg/ml.

Use at a concentration of 0.5 - 1 µg/ml to detect a limit of 0.06 ng/well of human TGFBR3.

WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 93.5 kDa.

This concentration is determined using 2 ng/lane of human TGFBR3 under non-reducing and reducing conditions

Target

  • FunctionBinds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
  • Sequence similaritiesContains 1 ZP domain.
  • Post-translational
    modifications
    Extensively modified by glycosaminoglycan groups (GAG).
  • Cellular localizationSecreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beta glycan antibody
    • Betaglycan antibody
    • Betaglycan proteoglycan antibody
    • BGCAN antibody
    • TGBR3_HUMAN antibody
    • TGF beta receptor type 3 antibody
    • TGF beta receptor type III antibody
    • TGF-beta receptor type 3 antibody
    • TGF-beta receptor type III antibody
    • TGFB R3 antibody
    • TGFBR 3 antibody
    • TGFBR3 antibody
    • TGFR 3 antibody
    • TGFR-3 antibody
    • TGFR3 antibody
    • Transforming growth factor beta receptor III antibody
    • Transforming growth factor beta receptor III betaglycan 300kDa antibody
    • Transforming growth factor beta receptor type 3 antibody
    see all

References for Anti-TGF beta Receptor III antibody (ab10854)

ab10854 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. The only option I found was ab28366- Rabbit polyclonal. Immunogen: Recombinant human TGF beta Receptor III protein encoding amino acids 644-850 expressed in E. coli. IHC-P. ab28367 (ready to use version of ab28366). ...

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Application Western blot
Sample Human Cell lysate - whole cell (Human Renal Proximal Tubular cells)
Loading amount 10 µg
Specification Human Renal Proximal Tubular cells
Gel Running Conditions Reduced Denaturing (12 %)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
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Dr. Robert Jenkins

Verified customer

Submitted May 14 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"