Anti-TGF beta Receptor III/TGFBR3 antibody (ab97459)
Key features and details
- Rabbit polyclonal to TGF beta Receptor III/TGFBR3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TGF beta Receptor III/TGFBR3 antibody
See all TGF beta Receptor III/TGFBR3 primary antibodies -
Description
Rabbit polyclonal to TGF beta Receptor III/TGFBR3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Pig -
Immunogen
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- NT2D1, IMR32, U87MG and MCF7 cell lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab97459 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 93 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 93 kDa. |
Target
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Function
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. -
Sequence similarities
Contains 1 ZP domain. -
Post-translational
modificationsExtensively modified by glycosaminoglycan groups (GAG). -
Cellular localization
Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. - Information by UniProt
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Database links
- Entrez Gene: 7049 Human
- Entrez Gene: 21814 Mouse
- Entrez Gene: 397512 Pig
- Entrez Gene: 29610 Rat
- Omim: 600742 Human
- SwissProt: Q03167 Human
- SwissProt: O88393 Mouse
- SwissProt: P35054 Pig
see all -
Alternative names
- Beta glycan antibody
- Betaglycan antibody
- Betaglycan proteoglycan antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab97459 has been referenced in 4 publications.
- Liu F et al. Distinct prognostic values and antitumor effects of tumor growth factor ß1 and its receptors in gastric cancer. Oncol Lett 20:2621-2632 (2020). PubMed: 32782580
- Yin Z et al. Macrophage-derived exosomal microRNA-501-3p promotes progression of pancreatic ductal adenocarcinoma through the TGFBR3-mediated TGF-ß signaling pathway. J Exp Clin Cancer Res 38:310 (2019). PubMed: 31307515
- Zakrzewski PK et al. Significance of TGFBR3 allelic loss in the deregulation of TGFß signaling in primary human endometrial carcinomas. Oncol Rep 35:932-8 (2016). PubMed: 26548418
- Priyadarsini S et al. Keratoconus in vitro and the key players of the TGF-ß pathway. Mol Vis 21:577-88 (2015). WB . PubMed: 26015770