Overview

  • Product name
  • Description
    Rabbit polyclonal to TGIF
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human TGIF aa 215-245 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q15583

  • Positive control
    • 293 cell lysates transiently transfected with the TGIF1 gene. Mouse bladder tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab170802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 43 kDa.

Target

  • Function
    Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.
  • Involvement in disease
    Holoprosencephaly 4
  • Sequence similarities
    Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5' TG 3' interacting factor antibody
    • 5''-TG-3''-interacting factor 1 antibody
    • Homeobox protein TGIF antibody
    • Homeobox protein TGIF1 antibody
    • HPE4 antibody
    • MGC39747 antibody
    • MGC5066 antibody
    • TALE homeobox TG-interacting factor antibody
    • TG interacting factor isoform c antibody
    • TG-interacting factor antibody
    • TGFB induced factor antibody
    • TGFB-induced factor homeobox 1 antibody
    • TGIF1 antibody
    • TGIF1_HUMAN antibody
    • transforming growth factor-beta-induced factor antibody
    see all

Images

  • Anti-TGIF antibody (ab170802) at 1/50 dilution + Mouse bladder tissue lysates at 35 µg

    Predicted band size : 43 kDa
  • All lanes : Anti-TGIF antibody (ab170802) at 1/50 dilution

    Lane 1 : Non-transfected 293 cell lysates
    Lane 2 : 293 cell lysates transiently transfected with the TGIF1 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 43 kDa

References

ab170802 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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