Overview

  • Product nameAnti-TH1L antibody
    See all TH1L primary antibodies
  • Description
    Goat polyclonal to TH1L
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    C-NKRVSINKDE

    , corresponding to internal sequence amino acids 373-382 of Human TH1L according to NP_945327.1

  • Positive control
    • Nuclear lysate from Jurkat cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab109587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 66 kDa).

Target

  • FunctionEssential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
  • Tissue specificityWidely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal and cardiac muscle, adrenal, thyroid, kidney and pancreas.
  • Sequence similaritiesBelongs to the NELF-D family.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HSPC130 antibody
    • Negative elongation factor C/D antibody
    • NELF C antibody
    • NELF D antibody
    • NELF-C/D antibody
    • NELFC antibody
    • NELFD antibody
    • NELFD_HUMAN antibody
    • TH1 antibody
    • TH1-like protein antibody
    • TH1L antibody
    see all

Anti-TH1L antibody images

References for Anti-TH1L antibody (ab109587)

ab109587 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"