Overview

  • Product name
  • Description
    Rabbit polyclonal to THADA
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: AHGHLQSATD TWENLVSDAR IKQGLIHQHC QVRIDTLGLL CESNRSTEIV SMEEMQWIQF FITYNLNSQS PGVRQQICSL LKKLFCRIQE SSQ, corresponding to amino acids 606-698 of Human THADA.

  • Positive control
    • Human duodenum tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

Target

  • Tissue specificity
    Expressed in pancreas, adrenal medulla, thyroid, adrenal cortex, testis, thymus, small intestine and stomach.
  • Involvement in disease
    Note=Chromosomal aberrations involving THADA have been observed in benign thyroid adenomas. Translocation t(2;3)(p21;p25) and translocation t(2;7)(p21;p15); the sequences derived from chromosomes 3p25 and 7p15 do not appear to include a coding region and the fusion events probably result in truncated THADA proteins.
  • Sequence similarities
    Belongs to the THADA family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Death receptor interacting protein antibody
    • Gene inducing thyroid adenomas protein antibody
    • GITA antibody
    • KIAA1767 antibody
    • THADA antibody
    • THADA_HUMAN antibody
    • Thyroid adenoma associated antibody
    • Thyroid adenoma-associated protein antibody
    see all

Images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in aggresome. Recommended concentration of ab122260 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122260, at 1/200, staining THADA in paraffin embedded Human duodenum tissue by Immunohistochemistry.

References

ab122260 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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