Overview

  • Product name
  • Description
    Rabbit polyclonal to THEM4
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide from Human THEM4, conjugated to KLH.

  • Positive control
    • Human kidney tissue; Human liver tissue lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113713 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
  • Tissue specificity
    Expressed predominantly in skeletal muscle, testis, uterus, brain and kidney. Down-regulated in glioblastoma or glioma compared to non-neoplastic brain due to promoter hypermethylation.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Cell membrane. Cell projection > ruffle membrane. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acyl CoA thioesterase THEM4 antibody
    • Acyl coenzyme A thioesterase THEM4 antibody
    • C terminal modulator protein antibody
    • Carboxyl-terminal modulator protein antibody
    • CTMP antibody
    • FLJ27206 antibody
    • MGC29636 antibody
    • OTTHUMP00000015248 antibody
    • Them4 antibody
    • THEM4_HUMAN antibody
    • Thioesterase superfamily member 4 antibody
    see all

Images

  • ab113713, at 5 µg/ml, staining THEM4 in formalin fixed, paraffin embedded Human kidney tissue by Immunohistochemistry.
  • Lane 1 : Anti-THEM4 antibody (ab113713) at 1 µg/ml
    Lane 2 : Anti-THEM4 antibody (ab113713) at 2 µg/ml

    Lane 1 : Human liver tissue lysate
    Lane 2 : Human liver tissue lysate


    Predicted band size : 27 kDa

References

ab113713 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab113713.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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