Overview

  • Product nameAnti-THG1L antibody
    See all THG1L primary antibodies
  • Description
    Rabbit polyclonal to THG1L
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • Immunogen

    Synthetic peptide, corresponding to N terminal amino acids 60-109 (RNFHRFAEEH NFAKPNDSRA HLMTKCAQTV EELEDIVIAY QSDEYSF) of Mouse THG1L (NP_001074438).

  • Positive control
    • Mouse spleen lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionAdds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
  • Tissue specificityExpressed in many tissues.
  • Sequence similaritiesBelongs to the tRNA(His) guanylyltransferase family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Found near the nuclear membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ICF45 antibody
    • Interphase cytoplasmic foci protein 45 antibody
    • Probable tRNA(His) guanylyltransferase antibody
    • THG1_HUMAN antibody
    • THG1L antibody
    • tRNA histidine guanylyltransferase 1 like (S. cerevisiae) antibody
    • tRNA-histidine guanylyltransferase antibody
    see all

Anti-THG1L antibody images

  • Anti-THG1L antibody (ab113879) at 1 µg/ml + Mouse spleen lysate at 10 µg

    Predicted band size : 35 kDa

References for Anti-THG1L antibody (ab113879)

ab113879 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"