Overview

  • Product nameAnti-THG1L antibody
    See all THG1L primary antibodies
  • Description
    Mouse polyclonal to THG1L
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length THG1L protein (Human) AAH23521.1

  • Positive control
    • ICF45 transfected 293T cell lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).

Target

  • FunctionAdds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
  • Tissue specificityExpressed in many tissues.
  • Sequence similaritiesBelongs to the tRNA(His) guanylyltransferase family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Found near the nuclear membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ICF45 antibody
    • Interphase cytoplasmic foci protein 45 antibody
    • Probable tRNA(His) guanylyltransferase antibody
    • THG1_HUMAN antibody
    • THG1L antibody
    • tRNA histidine guanylyltransferase 1 like (S. cerevisiae) antibody
    • tRNA-histidine guanylyltransferase antibody
    see all

Anti-THG1L antibody images

  • All lanes : Anti-THG1L antibody (ab69318) at 1/500 dilution

    Lane 1 : THG1L transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 34 kDa
    Observed band size : 34 kDa

References for Anti-THG1L antibody (ab69318)

ab69318 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"