Overview

  • Product name
  • Description
    Rabbit polyclonal to THG1L
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 179-228 of Human THG1L (NP_060342).

  • Positive control
    • Fetal spleen lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98225 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
  • Tissue specificity
    Expressed in many tissues.
  • Sequence similarities
    Belongs to the tRNA(His) guanylyltransferase family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Found near the nuclear membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ICF45 antibody
    • Interphase cytoplasmic foci protein 45 antibody
    • Probable tRNA(His) guanylyltransferase antibody
    • THG1_HUMAN antibody
    • THG1L antibody
    • tRNA histidine guanylyltransferase 1 like (S. cerevisiae) antibody
    • tRNA-histidine guanylyltransferase antibody
    see all

Images

  • Anti-THG1L antibody (ab98225) at 1 µg/ml + Human fetal spleen lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa

References

ab98225 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab98225.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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