Overview

  • Product nameAnti-ThPok antibody
    See all ThPok primary antibodies
  • Description
    Goat polyclonal to ThPok
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human ThPok.

  • Positive control
    • Human adrenal and testis tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab111211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionTranscription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes.
  • Sequence similaritiesContains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • c Krox antibody
    • cKrox antibody
    • DKFZp686G01254 antibody
    • hc Krox antibody
    • hcKrox antibody
    • Krueppel-related zinc finger protein cKrox antibody
    • Kruppel related zinc finger protein c Krox antibody
    • Kruppel related zinc finger protein cKrox antibody
    • Kruppel related zinc finger protein hcKrox antibody
    • T helper inducing POZ/Kruppel like factor antibody
    • T-helper-inducing POZ/Krueppel-like factor antibody
    • Th-POK antibody
    • ThPOK antibody
    • ZBT7B_HUMAN antibody
    • ZBTB 15 antibody
    • ZBTB 7B antibody
    • ZBTB15 antibody
    • ZBTB7B antibody
    • ZFP 67 antibody
    • Zfp-67 antibody
    • ZFP67 antibody
    • Zinc finger and BTB domain containing 15 antibody
    • Zinc finger and BTB domain containing 7B antibody
    • Zinc finger and BTB domain containing protein 15 antibody
    • Zinc finger and BTB domain containing protein 7B antibody
    • Zinc finger and BTB domain-containing protein 15 antibody
    • Zinc finger and BTB domain-containing protein 7B antibody
    • Zinc finger protein 67 homolog antibody
    • Zinc finger protein 857B antibody
    • Zinc finger protein Th POK antibody
    • Zinc finger protein Th-POK antibody
    • Zinc finger protein ThPOK antibody
    • ZNF857B antibody
    see all

Anti-ThPok antibody images

  • ab111211, at 3.75 µg/ml, staining ThPok in formalin fixed, paraffin embedded Human adrenal tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.
  • ab111211, at 3.75 µg/ml, staining ThPok in formalin fixed, paraffin embedded Human testis tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.

References for Anti-ThPok antibody (ab111211)

ab111211 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"