Overview

  • Product nameAnti-Thrombospondin 2 antibody
    See all Thrombospondin 2 primary antibodies
  • Description
    Rabbit polyclonal to Thrombospondin 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to an internal sequence of Human Thrombospondin 2.

Properties

Applications

Our Abpromise guarantee covers the use of ab112543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 130 kDa.

Target

  • FunctionAdhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
  • Tissue specificityHigh expression in invertebral disk tissue.
  • Involvement in diseaseGenetic variations in THBS2 may be a cause of susceptibility to intervertebral disc disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.
  • Sequence similaritiesBelongs to the thrombospondin family.
    Contains 3 EGF-like domains.
    Contains 1 TSP C-terminal (TSPC) domain.
    Contains 1 TSP N-terminal (TSPN) domain.
    Contains 3 TSP type-1 domains.
    Contains 8 TSP type-3 repeats.
    Contains 1 VWFC domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • THBS2 antibody
    • Thrombospondin-2 antibody
    • TSP2 antibody
    • TSP2_HUMAN antibody

Anti-Thrombospondin 2 antibody images

  • All lanes : Anti-Thrombospondin 2 antibody (ab112543)

    Lane 1 : SMMC whole cell lysate
    Lane 2 : MCF-7 whole cell lysate
    Lane 3 : HT1080 whole cell lysate
    Lane 4 : Jurkat whole cell lysate


    Predicted band size : 130 kDa
    Observed band size : 130 kDa
    Additional bands at : 100 kDa,110 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Thrombospondin 2 antibody (ab112543)

ab112543 has not yet been referenced specifically in any publications.

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