Anti-Thrombospondin 2 antibody [MM0568-9T19] (ab89805)
Key features and details
- Mouse monoclonal [MM0568-9T19] to Thrombospondin 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG2
Overview
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Product name
Anti-Thrombospondin 2 antibody [MM0568-9T19]
See all Thrombospondin 2 primary antibodies -
Description
Mouse monoclonal [MM0568-9T19] to Thrombospondin 2 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length Human Thrombospondin 2
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Positive control
- WB: Human placenta tissue lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter. -
Clonality
Monoclonal -
Clone number
MM0568-9T19 -
Isotype
IgG2 -
Research areas
Associated products
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Compatible Secondaries
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab89805 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 130 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 130 kDa. |
Target
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Function
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. -
Tissue specificity
High expression in invertebral disk tissue. -
Involvement in disease
Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disc disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain. -
Sequence similarities
Belongs to the thrombospondin family.
Contains 3 EGF-like domains.
Contains 1 TSP C-terminal (TSPC) domain.
Contains 1 TSP N-terminal (TSPN) domain.
Contains 3 TSP type-1 domains.
Contains 8 TSP type-3 repeats.
Contains 1 VWFC domain. - Information by UniProt
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Database links
- Entrez Gene: 7058 Human
- Omim: 188061 Human
- SwissProt: P35442 Human
- Unigene: 371147 Human
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Alternative names
- THBS2 antibody
- Thrombospondin-2 antibody
- TSP2 antibody
- TSP2_HUMAN antibody
Images
Datasheets and documents
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Datasheet download
References (1)
ab89805 has been referenced in 1 publication.
- Dong XH et al. Chronic Exposure to Subtherapeutic Antibiotics Aggravates Ischemic Stroke Outcome in Mice. EBioMedicine 24:116-126 (2017). WB ; Mouse . PubMed: 28928014