Anti-Thrombospondin 2 antibody [MM0568-9T19] (ab89805)

Overview

  • Product nameAnti-Thrombospondin 2 antibody [MM0568-9T19]
    See all Thrombospondin 2 primary antibodies
  • Description
    Mouse monoclonal [MM0568-9T19] to Thrombospondin 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human Thrombospondin 2

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • ClonalityMonoclonal
  • Clone numberMM0568-9T19
  • IsotypeIgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 130 kDa.

Target

  • FunctionAdhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
  • Tissue specificityHigh expression in invertebral disk tissue.
  • Involvement in diseaseGenetic variations in THBS2 may be a cause of susceptibility to intervertebral disc disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.
  • Sequence similaritiesBelongs to the thrombospondin family.
    Contains 3 EGF-like domains.
    Contains 1 TSP C-terminal (TSPC) domain.
    Contains 1 TSP N-terminal (TSPN) domain.
    Contains 3 TSP type-1 domains.
    Contains 8 TSP type-3 repeats.
    Contains 1 VWFC domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • THBS2 antibody
    • Thrombospondin-2 antibody
    • TSP2 antibody
    • TSP2_HUMAN antibody

References for Anti-Thrombospondin 2 antibody [MM0568-9T19] (ab89805)

ab89805 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: Rt°C
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Tris pH 9.0 and 10mM Sodium Citrate
Sample Human Tissue sections (various human tissues)
Specification various human tissues
Permeabilization Yes - 0.2% Triton X-100 and PBS
Fixative Formaldehyde
Username

Dr. Steffen Rickelt

Verified customer

Submitted Mar 14 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"