Anti-Thromboxane A2 receptor antibody (ab92883)

Overview

  • Product nameAnti-Thromboxane A2 receptor antibody
    See all Thromboxane A2 receptor primary antibodies
  • Description
    Rabbit polyclonal to Thromboxane A2 receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide:

    LSTRPRSLSLQPQLTQRSGLQ

    , corresponding to amino acids 323-343 of Human Thromboxane A2 receptor.

  • Positive control
    • Jurkat, ECL, SGC cell lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab92883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/5000. Detects a band of approximately 55 kDa (predicted molecular weight: 40 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.
    • Involvement in diseaseDefects in TBXA2R are the cause of susceptibility to bleeding disorder platelet-type 13 (BDPLT13) [MIM:614009]. BDPLT13 is a disorder characterized by reduced platelet aggregation and a tendency to mild mucocutaneous bleeding.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • BDPLT13 antibody
      • Prostanoid TP receptor antibody
      • TA2R_HUMAN antibody
      • Tbxa2r antibody
      • Thromboxane A2 receptor antibody
      • TP receptor antibody
      • TXA2 R antibody
      • TXA2-R antibody
      • TXA2R antibody
      see all

    Anti-Thromboxane A2 receptor antibody images

    • All lanes : Anti-Thromboxane A2 receptor antibody (ab92883) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate at 43 µg
      Lane 2 : ECL cell lysate at 67 µg
      Lane 3 : SGC cell lysate at 55 µg


      Predicted band size : 40 kDa
      Observed band size : 55 kDa (why is the actual band size different from the predicted?)

    References for Anti-Thromboxane A2 receptor antibody (ab92883)

    ab92883 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. We do not currently have any Thromboxone A2 receptor proteins or peptides in our catalog.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.<...

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    Thank you for contacting us. Yes, this antibody can be used with mouse samples. The other anti-Thromboxane A2 receptor antibody (ab85544) has not been tested with mouse. We are currently not aware of any publications or references that have used the an...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"