Recombinant
RabMAb

Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)

Overview

  • Product name
    Anti-Thromboxane synthase antibody [EPR7333(2)]
    See all Thromboxane synthase primary antibodies
  • Description
    Rabbit monoclonal [EPR7333(2)] to Thromboxane synthase
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Thromboxane synthase (UniProt P24557).

  • Positive control
    • WI38 and fetal liver lysates.
  • General notes

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Associated products

Applications

Our Abpromise guarantee covers the use of ab157481 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 61 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Tissue specificity
      Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
    • Involvement in disease
      Defects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.
      Defects in TBXAS1 are the cause of thromboxane synthetase deficiency (TBXAS1 deficiency) [MIM:274180]. It is characterized by hemorrhagic diathesis.
    • Sequence similarities
      Belongs to the cytochrome P450 family.
    • Cellular localization
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • BDPLT14 antibody
      • CYP5 antibody
      • CYP5A1 antibody
      • Cytochrome P450 5A1 antibody
      • Cytochrome P450, family 5, subfamily A, polypeptide 1 antibody
      • FLJ52771 antibody
      • GHOSAL antibody
      • Platelet cytochrome P450 subfamily V antibody
      • Tbxas1 antibody
      • THAS antibody
      • THAS_HUMAN antibody
      • Thromboxane A synthase 1 (platelet) antibody
      • Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) antibody
      • Thromboxane A synthase 1 antibody
      • Thromboxane A synthase 1 platelet cytochrome P450 subfamily V antibody
      • Thromboxane-A synthase antibody
      • TS antibody
      • TXA synthase antibody
      • TXAS antibody
      • TXS antibody
      see all

    Images

    • All lanes : Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481) at 1/1000 dilution

      Lane 1 : WI38 cell lysate
      Lane 2 : Fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 61 kDa

    References

    ab157481 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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