Anti-Thromboxane synthase antibody [Tü-300] (Biotin) (ab15623)

Overview

  • Product nameAnti-Thromboxane synthase antibody [Tü-300] (Biotin)
    See all Thromboxane synthase primary antibodies
  • Description
    Mouse monoclonal [Tü-300] to Thromboxane synthase (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: IHC-Frmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Does not react with: Rat
  • Immunogen

    Full length native protein (purified human Thromboxane synthase).

  • General notesAliquots of stock solution can be kept frozen at -80°C; do not freeze working dilutions. Caution: this product contains Thimerosal, a poisonous and hazardous substance.


    Tü 300 is a useful marker for the detection of native thromboxane synthase in smears, isolated cells, human tissue sections, and for affinity purification of the enzyme.

Properties

Applications

Our Abpromise guarantee covers the use of ab15623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use a concentration of 2 µg/ml.
  • Application notesIs unsuitable for WB.
  • Target

    • Tissue specificityPlatelets, lung, kidney, spleen, macrophages and lung fibroblasts.
    • Involvement in diseaseDefects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.
      Defects in TBXAS1 are the cause of thromboxane synthetase deficiency (TBXAS1 deficiency) [MIM:274180]. It is characterized by hemorrhagic diathesis.
    • Sequence similaritiesBelongs to the cytochrome P450 family.
    • Cellular localizationEndoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • BDPLT14 antibody
      • CYP5 antibody
      • CYP5A1 antibody
      • Cytochrome P450 5A1 antibody
      • Cytochrome P450, family 5, subfamily A, polypeptide 1 antibody
      • FLJ52771 antibody
      • GHOSAL antibody
      • Platelet cytochrome P450 subfamily V antibody
      • Tbxas1 antibody
      • THAS antibody
      • THAS_HUMAN antibody
      • Thromboxane A synthase 1 (platelet) antibody
      • Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) antibody
      • Thromboxane A synthase 1 antibody
      • Thromboxane A synthase 1 platelet cytochrome P450 subfamily V antibody
      • Thromboxane-A synthase antibody
      • TS antibody
      • TXA synthase antibody
      • TXAS antibody
      • TXS antibody
      see all

    References for Anti-Thromboxane synthase antibody [Tü-300] (Biotin) (ab15623)

    ab15623 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"