Feedback Form

Product Name 

Thyroglobulin antibody [12G9]

 

See all Thyroglobulin antibodies (19)...

Product type 

Primary antibodies

Description 

Mouse monoclonal [12G9] to Thyroglobulin

Immunogen 

Thyroglobulin from human thyroid gland.

Reacts with 
(species key)

Hu, Ms, Rat, Cat, Cow, Dog, Pig

Specificity 

This antibody does not interfere with anti-thyroglobulin autoantibodies.

Tested applications 
(see key)

ELISA


Abreviews 

Customer reviews
(see key)


Read about Abreviews

Submit an Abreview

Be the first to review this product and earn 220 Abpoints.


Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Secreted

Research areas 

Cancer >> Tumor biomarkers >> Globulins
Signal Transduction >> Growth Factors/Hormones >> Hormones

Relevance 

Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

 

Alternative names Thyroglobulin antibody [12G9] (ab1983)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

280706    (Cow)
7038    (Human)
21819    (Mouse)
24826    (Rat)

Omim

    

188450    (Human)

SwissProt

    

P01267    (Cow)
P01266    (Human)
O08710    (Mouse)
P06882    (Rat)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

12G9

Myeloma 

Sp2/0

Isotype 

IgM

Purity 

Protein G purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purity is tested by electrophoresis.

Form 

Liquid

Concentration 

5.000 mg/ml

Storage instructions 

Store at +4°C.

Notes 

Concentration varies from lot to lot and can be provided on request.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Thyroglobulin antibody [12G9] is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to Thyroglobulin

 

Thyroglobulin antibody [12G9] - more information

Customer reviews (feedback) regarding Thyroglobulin antibody [12G9]

Customer FAQs regarding Thyroglobulin antibody [12G9]

Protocols for Thyroglobulin antibody [12G9]

Price and availability of products related to Thyroglobulin antibody [12G9]

 

Thyroglobulin antibody [12G9] - related products:

 

Compatible IgM Secondary for Thyroglobulin antibody [12G9]

ab8516

  

Rabbit polyclonal Secondary Antibody to Mouse IgG+IgM+IgA

ab8517

  

Rabbit polyclonal Secondary Antibody to Mouse IgG+IgM+IgA (FITC)

ab8518

  

Rabbit polyclonal Secondary Antibody to Mouse IgG+IgM+IgA (HRP)

ab9167

  

Goat polyclonal Secondary Antibody to Mouse IgM

ab9175

  

Rabbit polyclonal Secondary Antibody to Mouse IgM - mu chain

 

Compatible Secondaries for Thyroglobulin antibody [12G9]

ab2891

  

HRP polymer antibody

ab6563

  

Cy5 ® antibody

ab6726

  

Texas Red ® antibody

ab6728

  

HRP antibody

ab6729

  

Alkaline Phosphatase antibody

ab6785

  

FITC antibody

ab6788

  

Biotin antibody

ab7002

  

Phycoerythrin antibody

ab7018

  

Agarose antibody

ab27229

  

15nm Gold antibody

ab27230

  

10nm Gold antibody

ab27231

  

15nm Gold antibody

ab27233

  

5nm Gold antibody

ab27241

  

10nm Gold antibody

ab27242

  

20nm Gold antibody

ab27243

  

40nm Gold antibody

ab27244

  

5nm Gold antibody

ab60313

  

Chromeo™ 488 antibody

ab60316

  

Chromeo™ 546 antibody

ab60318

  

Chromeo™ 642 antibody

ab79091

  

Rat monoclonal [SB84a] Secondary Antibody to Mouse IgG2a - gamma chain

 

Other Thyroglobulin Antibodies

See all Thyroglobulin antibodies (19)...

 

Thyroglobulin antibody [12G9] - other tools:

Contact Abcam with a Technical Enquiry about Thyroglobulin antibody [12G9]

 

All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"