Recombinant
RabMAb

Anti-Thyroid Hormone Receptor alpha antibody [EPR7862] (ab179438)

Overview

  • Product name
    Anti-Thyroid Hormone Receptor alpha antibody [EPR7862]
    See all Thyroid Hormone Receptor alpha primary antibodies
  • Description
    Rabbit monoclonal [EPR7862] to Thyroid Hormone Receptor alpha
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Thyroid Hormone Receptor alpha aa 400 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: P10827

  • Positive control
    • Jurkat, Molt-4 and MCF-7 cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab179438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 55 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function
      Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
    • Involvement in disease
      Hypothyroidism, congenital, non-goitrous, 6
    • Sequence similarities
      Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • Domain
      Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AR7 antibody
      • c-erbA-1 antibody
      • C-erbA-alpha antibody
      • CHNG6 antibody
      • EAR-7 antibody
      • EAR7 antibody
      • ERB-T-1 antibody
      • ERBA antibody
      • ERBA-related 7 antibody
      • ERBA1 antibody
      • NR1A1 antibody
      • Nuclear receptor subfamily 1 group A member 1 antibody
      • THA_HUMAN antibody
      • THRA antibody
      • THRA1 antibody
      • THRA2 antibody
      • Thyroid hormone receptor alpha antibody
      • thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) antibody
      • thyroid normone nuclear receptor alpha variant 1 antibody
      • triiodothyronine receptor antibody
      • V-erbA-related protein 7 antibody
      see all

    Images

    • All lanes : Anti-Thyroid Hormone Receptor alpha antibody [EPR7862] (ab179438) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : Molt-4 cell lysate
      Lane 3 : MCF-7 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 55 kDa

    References

    ab179438 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab179438.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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