Anti-Thyroid Hormone Receptor beta 1 antibody (ab155297)

Overview

  • Product name
    Anti-Thyroid Hormone Receptor beta 1 antibody
    See all Thyroid Hormone Receptor beta 1 primary antibodies
  • Description
    Rabbit polyclonal to Thyroid Hormone Receptor beta 1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-199 of Human Thyroid Hormone Receptor beta 1 (UniProt: P10828).

  • Positive control
    • 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates; Hela cells
  • General notes
    Keep as a concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155297 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Relevance
    Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3 triiodo L thyronine (T3). Thyroid hormones, through their interaction with the thyroid receptor (TR), effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2 antibody
    • C ERBA 2 antibody
    • C ERBA BETA antibody
    • ERBA 2 antibody
    • ERBA BETA antibody
    • ERBA2 antibody
    • Erythroblastic leukemia viral (v erb a) oncogene homolog 2 avian antibody
    • GRTH antibody
    • MGC126109 antibody
    • MGC126110 antibody
    • NR1A2 antibody
    • Nuclear receptor subfamily 1 group A member 2 antibody
    • oncogene ERBA2 antibody
    • PRTH antibody
    • THR 1 antibody
    • THR1 antibody
    • THRB 1 antibody
    • THRB1 antibody
    • THRB2 antibody
    • Thyroid hormone nuclear receptor beta variant 1 antibody
    • thyroid hormone receptor beta antibody
    • Thyroid hormone receptor, beta (erythroblastic leukemia viral (v erb a) oncogene homolog 2, avian) antibody
    see all

Images

  • Anti-Thyroid Hormone Receptor beta 1 antibody (ab155297) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 53 kDa



    10% SDS PAGE
  • Immunofluorescence analysis of paraformaldehyde fixed HeLa cells labeling Thyroid Hormone Receptor beta 1 using ab155297 at 1/200. Lower image shows co-staining with a DNA probe.

References

ab155297 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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