Recombinant
RabMAb

Anti-TIAL1 antibody [EPR11324(B)] (ab155973)

Overview

  • Product name
    Anti-TIAL1 antibody [EPR11324(B)]
    See all TIAL1 primary antibodies
  • Description
    Rabbit monoclonal [EPR11324(B)] to TIAL1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human TIAL1 (UniProt ID: Q01085).

  • Positive control
    • HeLa and Jurkat cell lysates; Jurkat cells.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab155973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 42 kDa.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
    • Sequence similarities
      Contains 3 RRM (RNA recognition motif) domains.
    • Post-translational
      modifications
      Phosphorylated by MAPK14 following DNA damage, releasing TIAR from GADD45A mRNA.
    • Cellular localization
      Cytoplasm. Nucleus. Cytoplasmic granule. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Cytoplasmic granules of cytolytic T-lymphocytes.
    • Information by UniProt
    • Database links
    • Alternative names
      • Aging associated gene 7 protein antibody
      • Nucleolysin TIAR antibody
      • T cluster binding protein antibody
      • TCBP antibody
      • TIA 1 related nucleolysin antibody
      • TIA-1-related protein antibody
      • TIA1 cytotoxic granule associated RNA binding protein like 1 antibody
      • TIA1 related protein antibody
      • TIAL1 antibody
      • TIAR antibody
      • TIAR_HUMAN antibody
      see all

    Images

    • All lanes : Anti-TIAL1 antibody [EPR11324(B)] (ab155973) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 42 kDa

    • Flow cytometry analysis of permeabilized Jurkat cells labeling TIAL1 (red), using ab155973 at a 1/10 dilution, and negative control cells (green) probed with a Rabbit IgG.

    References

    ab155973 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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