• Product nameAnti-TID1 antibody
    See all TID1 primary antibodies
  • Description
    Rabbit polyclonal to TID1
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment containing a sequence corresponding to a region within amino acids 1-406 of Human TID1.(Uniprot: Q96EY1)

  • Positive control
    • HeLa cell lysate, HepG2 cell lysate and HCT116 cell lysate.



Our Abpromise guarantee covers the use of ab125701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 52 kDa.
ICC/IF 1/100 - 1/1000.


  • RelevanceTID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localized splice variants of human Tid1 designated hTid1S and hTid1L. These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70. They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity. Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha. A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis. Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected. It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities. Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.
  • Cellular localizationMitochondrial
  • Database links
  • Alternative names
    • DnaJ (Hsp40) homolog subfamily A member 3 antibody
    • DnaJ homolog subfamily A member 3 mitochondrial precursor antibody
    • DnaJ protein Tid 1 antibody
    • DnaJ protein Tid1 antibody
    • FLJ45758 antibody
    • HCA57 antibody
    • Hepatocellular carcinoma associated antigen 57 antibody
    • Highly similar to HYPOTHETICAL 105.9 KD PROTEIN F22B7.5 IN CHROMOSOME antibody
    • hTid 1 antibody
    • hTid1 antibody
    • III [Caenorhabditis elegans] antibody
    • TID1 antibody
    • Tumorous imaginal discs (Drosophila) homolog antibody
    • Tumorous imaginal discs protein Tid56 homolog antibody
    see all

Anti-TID1 antibody images

  • ab125701, at 1/500 dilution, staining TID1 (Green) in Methanol-fixed HeLa cells by Immunocytochemistry/Immunofluorescence.
  • All lanes : Anti-TID1 antibody (ab125701) at 1/1000 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : HCT116 cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 52 kDa

References for Anti-TID1 antibody (ab125701)

ab125701 has not yet been referenced specifically in any publications.

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