Overview

  • Product nameAnti-TIE1 antibody
    See all TIE1 primary antibodies
  • Description
    Rabbit polyclonal to TIE1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to C terminus of human TIE1

  • Positive control
    • Human tonsil tissue
  • General notesCell membrane staining pattern

Properties

Applications

Our Abpromise guarantee covers the use of ab64477 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 for 30 min at room temperature.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionTransmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
    • Tissue specificitySpecifically expressed in developing vascular endothelial cells.
    • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
      Contains 3 EGF-like domains.
      Contains 3 fibronectin type-III domains.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • JKT 14 antibody
      • JTK14 antibody
      • TIE antibody
      • Tie1 antibody
      • TIE1_HUMAN antibody
      • Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 antibody
      • Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains antibody
      • Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody
      • Tyrosine protein kinase receptor Tie 1 antibody
      • Tyrosine-protein kinase receptor Tie-1 antibody
      see all

    Anti-TIE1 antibody images

    • ab64477, at a dilution of 1/100, staining TIE1 in formalin fixed, paraffin embedded human tonsil tissue sections by Immunohistochemistry.

    References for Anti-TIE1 antibody (ab64477)

    ab64477 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. Unfortunately, I am sorry we are not able to release the immunogen sequence for this particular antibody as it is considered commercially sensitive. However, our source for this antibody has confirmed that the sequen...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"