Overview

  • Product name
    Anti-TIE1 antibody, prediluted
    See all TIE1 primary antibodies
  • Description
    Rabbit polyclonal to TIE1, prediluted
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to C terminal of human TIE1.

  • Positive control
    • Human tonsil

Properties

Applications

Our Abpromise guarantee covers the use of ab64488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Ready to use for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
    • Tissue specificity
      Specifically expressed in developing vascular endothelial cells.
    • Sequence similarities
      Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
      Contains 3 EGF-like domains.
      Contains 3 fibronectin type-III domains.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • JKT 14 antibody
      • JTK14 antibody
      • TIE antibody
      • Tie1 antibody
      • TIE1_HUMAN antibody
      • Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 antibody
      • Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains antibody
      • Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody
      • Tyrosine protein kinase receptor Tie 1 antibody
      • Tyrosine-protein kinase receptor Tie-1 antibody
      see all

    Images

    • ab64488, prediluted, staining TIE1 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

    References

    ab64488 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab64488.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up