Macrolide antibiotic agent. Inhibits protein synthesis. Shows more potent effects against Gram-positive bacteria than Gram-negative strains (MIC values are 7 and 58 μM for Streptococcus suis, Actinomyces pyogenes and Gram-negative strains respectively) in vivo. Orally active.
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in water to 5 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Abdel-Daim MM et al. Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. Can J Physiol Pharmacol93:45-51 (2015).
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Chen X et al. Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes. Int J Nanomedicine9:2655-64 (2014).
Read more (PubMed: 24920902) »
Jordan FT & Horrocks BK The minimum inhibitory concentration of tilmicosin and tylosin for mycoplasma gallisepticum and Mycoplasma synoviae and a comparison of their efficacy in the control of Mycoplasma gallisepticum infection in broiler chicks. Avian Dis40:326-34 (0).
Read more (PubMed: 8790882) »