Overview

  • Product nameAnti-TIMM17B antibody
  • Description
    Rabbit polyclonal to TIMM17B
  • Tested applicationsSuitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: ILLALIEGVG ILLTRYTAQQ FRNAPPFLED PSQLPPKDGT PAPGYPSYQQ YH, corresponding to C terminal amino acids 121-172 of Human TIMM17B.

  • Positive control
    • Human bone marrow tissue. Lysate from RT4 and U-251 MG cells. Human cell line U-2 OS.

Properties

Applications

Our Abpromise guarantee covers the use of ab122034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

Target

  • FunctionEssential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
  • Tissue specificityExpression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver.
  • Sequence similaritiesBelongs to the Tim17/Tim22/Tim23 family.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DXS9822 antibody
    • Inner mitochondrial membrane preprotein translocase antibody
    • JM3 antibody
    • Mitochondrial import inner membrane translocase subunit Tim17-B antibody
    • TI17B_HUMAN antibody
    • Tim17b antibody
    • TIMM17B antibody
    • Translocase of inner mitochondrial membrane 17 homolog B (yeast) antibody
    see all

Anti-TIMM17B antibody images

  • ab122034 at 1/85 dilution staining TIMM17B in paraffin-embedded Human bone marrow tissue by Immunohistochemistry.
  • ab122034 at 4 µg/ml staining TIMM17B in Human cell line U-2 OS by Immunofluorescence. Antibody staining is shown in green.
  • All lanes : Anti-TIMM17B antibody (ab122034) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver tissue lysate
    Lane 5 : Human tonsil tissue lysate

References for Anti-TIMM17B antibody (ab122034)

ab122034 has not yet been referenced specifically in any publications.

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