Overview

  • Product nameAnti-TL1A antibody
    See all TL1A primary antibodies
  • Description
    Rabbit polyclonal to TL1A
  • SpecificityIt will not cross-react with TL1.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 14 amino acids near the N-terminus of TL1A. The immunogen sequence has been taken from within amino acids 50-100.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab21272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 28 kDa.

Target

  • FunctionReceptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
  • Tissue specificitySpecifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Cellular localizationSecreted and Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC129934 antibody
    • MGC129935 antibody
    • TL1 A antibody
    • tl1 antibody
    • tl1a antibody
    • tnf ligand related molecule 1 antibody
    • TNF ligand-related molecule 1 antibody
    • tnf superfamily ligand tl1a antibody
    • TNF15_HUMAN antibody
    • TNFSF15 antibody
    • Tumor necrosis factor (ligand) superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15, secreted form antibody
    • Vascular endothelial cell growth inhibitor antibody
    • Vascular endothelial growth inhibitor 192a antibody
    • Vascular endothelial growth inhibitor antibody
    • vegi antibody
    • VEGI192A antibody
    see all

Anti-TL1A antibody images

  • Lane 1 : Anti-TL1A antibody (ab21272) at 0.5 µg/ml
    Lane 2 : Anti-TL1A antibody (ab21272) at 1 µg/ml
    Lane 3 : Anti-TL1A antibody (ab21272) at 2 µg/ml

    Lane 1 : PC-3 cell lysate
    Lane 2 : PC-3 cell lysate
    Lane 3 : PC-3 cell lysate


    Predicted band size : 28 kDa

References for Anti-TL1A antibody (ab21272)

This product has been referenced in:

See 1 Publication for this product

Product Wall

Thank you for contacting us. I believe we discussed this on the phone earlier today.

To recap, this antibody was raised against a linear synthetic peptide and has only been tested in reduced, denatured conditions. While it may work under non-...

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Thank you for contacting us. Regarding a secondary antibody, any anti-rabbit secondary, including the one you have, should work well with this antibody. The lysate tested for Western Blotting is PC3, and is available as a lysate in our catalog as ab395...

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Thank you for your enquiry. Jen is outof the office this week, so I cam handling some of her enquiries. The PC3 cells were not treated with protease inhibitors during culture, but there is leupeptin and aprotinin in the lysate (5ug/mL). Please see...

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Thank you for your email. A metaloprotease inhibitor wasn't used, but there was leupeptin and aprotinin in the lysate (5ug/mL). The PC-3 whole cell lysate that was used (we sell this same one, it is catalog# ab3954) by the antibody's originator was pre...

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Thank you for the protocol details that you have provided and I'm sorry to hear that you're experiencing difficulty with ab21272. The antibody was characterized for application in Western blotting using PC-3 cell lysate and quite a strong band was dete...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"