Overview

  • Product name
    Anti-TL1A antibody
    See all TL1A primary antibodies
  • Description
    Rabbit polyclonal to TL1A
  • Host species
    Rabbit
  • Specificity
    Detects endogenous levels of total TL1A protein.
  • Tested applications
    Suitable for: WB, ICC/IF, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide C-terminal of human TNFSF15.

  • Positive control
    • COLO205 cell extract HeLa cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab64986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).
ICC/IF 1/500 - 1/1000.
ELISA 1/20000.

Target

  • Function
    Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
  • Tissue specificity
    Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
  • Sequence similarities
    Belongs to the tumor necrosis factor family.
  • Cellular localization
    Secreted and Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • MGC129934 antibody
      • MGC129935 antibody
      • TL1 A antibody
      • tl1 antibody
      • tl1a antibody
      • tnf ligand related molecule 1 antibody
      • TNF ligand-related molecule 1 antibody
      • tnf superfamily ligand tl1a antibody
      • TNF15_HUMAN antibody
      • TNFSF15 antibody
      • Tumor necrosis factor (ligand) superfamily member 15 antibody
      • Tumor necrosis factor ligand superfamily member 15 antibody
      • Tumor necrosis factor ligand superfamily member 15, secreted form antibody
      • Vascular endothelial cell growth inhibitor antibody
      • Vascular endothelial growth inhibitor 192a antibody
      • Vascular endothelial growth inhibitor antibody
      • vegi antibody
      • VEGI192A antibody
      see all

    Images

    • Western blot - Anti-TL1A antibody (ab64986)
      Western blot - Anti-TL1A antibody (ab64986)
      All lanes : Anti-TL1A antibody (ab64986) at 1/500 dilution

      Lane 1 : COLO205 cell extract
      Lane 2 : COLO205 cell extract with immunising peptide at 10 µg

      Lysates/proteins at 30 µg per lane.

      Predicted band size: 20 kDa
      Observed band size: 20 kDa

    • Immunocytochemistry/ Immunofluorescence - Anti-TL1A antibody (ab64986)
      Immunocytochemistry/ Immunofluorescence - Anti-TL1A antibody (ab64986)
      Immunofluorescence analysis of HeLa cells, using ab64986 at 1/500-1/1000 dilution. Right hand panel was also treated with immunising peptide.

    References

    ab64986 has not yet been referenced specifically in any publications.

    Publishing research using ab64986? Please let us know so that we can cite the reference in this datasheet.

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