Overview

  • Product name
    Anti-TLR1 antibody - N-terminal
    See all TLR1 primary antibodies
  • Description
    Rabbit polyclonal to TLR1 - N-terminal
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human TLR1 (N terminal). The exact sequence is proprietary.
    Database link: Q15399

  • Positive control
    • Mouse spleen lysate; mouse spleen tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab195439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 90 kDa.
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Tissue specificity
    Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
  • Sequence similarities
    Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localization
    Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD281 antibody
    • CD281 antigen antibody
    • KIAA0012 antibody
    • LPRS5 antibody
    • rsc786 antibody
    • TIL antibody
    • TIL. LPRS5 antibody
    • Tlr1 antibody
    • TLR1_HUMAN antibody
    • Toll (Drosophila) homolog antibody
    • Toll like receptor 1 antibody
    • Toll-like receptor 1 antibody
    • Toll/interleukin-1 receptor-like protein antibody
    see all

Images

  • Lane 1 : Anti-TLR1 antibody - N-terminal (ab195439) at 1 µg/ml
    Lane 2 : Anti-TLR1 antibody - N-terminal (ab195439) at 2 µg/ml
    Lane 3 : Anti-TLR1 antibody - N-terminal (ab195439) at 4 µg/ml

    Lane 1 : Mouse spleen lysate
    Lane 2 : Mouse spleen lysate
    Lane 3 : Mouse spleen lysate


    Predicted band size : 90 kDa
  • Immunohistochemical analysis of mouse spleen tissue, labeling TLR1 with ab195439 at 10 µg/ml.

References

ab195439 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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