Overview

  • Product name
    Anti-TLR10 antibody [3C10C5]
    See all TLR10 primary antibodies
  • Description
    Mouse monoclonal [3C10C5] to TLR10
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to extracellular domain amino acids 20-474 of Human TLR10 (NP_001017388 ).

Properties

Applications

Our Abpromise guarantee covers the use of ab113446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Tissue specificity
    Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
  • Sequence similarities
    Belongs to the Toll-like receptor family.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 290 antibody
    • CD 290 antigen antibody
    • CD290 antibody
    • CD290 antigen antibody
    • MGC104967 antibody
    • MGC126398 antibody
    • MGC126399 antibody
    • OTTHUMP00000158729 antibody
    • OTTHUMP00000218162 antibody
    • TLR10 antibody
    • TLR10_HUMAN antibody
    • Toll like receptor 10 antibody
    • Toll-like receptor 10 antibody
    • UNQ315/PRO358 antibody
    see all

References

ab113446 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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