Overview

  • Product name
  • Description
    Rabbit polyclonal to TLR10
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to 14 amino acids near the middle of TLR10 (Human).

  • Positive control
    • Human lymph node cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab21273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 94 kDa.Can be blocked with Active human TLR10 peptide (ab39866).
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function
    Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Tissue specificity
    Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
  • Sequence similarities
    Belongs to the Toll-like receptor family.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 290 antibody
    • CD 290 antigen antibody
    • CD290 antibody
    • CD290 antigen antibody
    • MGC104967 antibody
    • MGC126398 antibody
    • MGC126399 antibody
    • OTTHUMP00000158729 antibody
    • OTTHUMP00000218162 antibody
    • TLR10 antibody
    • TLR10_HUMAN antibody
    • Toll like receptor 10 antibody
    • Toll-like receptor 10 antibody
    • UNQ315/PRO358 antibody
    see all

Images

  • Lane 1 : Anti-TLR10 antibody (ab21273) at 0.5 µg/ml
    Lane 2 : Anti-TLR10 antibody (ab21273) at 1 µg/ml

    Lane 1 : Human lymph node cell lysates
    Lane 2 : Human lymph node cell lysates


    Predicted band size : 94 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)

References

ab21273 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab21273.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up